Fadhil, O., Gorial, F. (2023). Medications’ Adherence amongst a Sample of Patients with Ankylosing Spondylitis. Alustath, 22(1), 33-40. doi: 10.52573/ipmj.2023.179272
Omar S. Fadhil; Faiq I. Gorial. "Medications’ Adherence amongst a Sample of Patients with Ankylosing Spondylitis". Alustath, 22, 1, 2023, 33-40. doi: 10.52573/ipmj.2023.179272
Fadhil, O., Gorial, F. (2023). 'Medications’ Adherence amongst a Sample of Patients with Ankylosing Spondylitis', Alustath, 22(1), pp. 33-40. doi: 10.52573/ipmj.2023.179272
Fadhil, O., Gorial, F. Medications’ Adherence amongst a Sample of Patients with Ankylosing Spondylitis. Alustath, 2023; 22(1): 33-40. doi: 10.52573/ipmj.2023.179272

Medications’ Adherence amongst a Sample of Patients with Ankylosing Spondylitis

Iraqi Postgraduate Medical Journal
Volume 22, Issue 1, January 2023, Pages 33-40    PDF (5.91 M)
DOI: 10.52573/ipmj.2023.179272
Authors
Omar S. Fadhil1; Faiq I. Gorial2
1Rheumatology Unit, Baghdad Teaching Hospital, Baghdad, Iraq.
2Rheumatology Unit, Department of Medicine, College of Medicine, University of Baghdad, Baghdad, Iraq.
Abstract
BACKGROUND:
Ankylosing spondylitis is a chronic progressive inflammatory disease affecting spine and other joints leads to great disability and chronic pain, and has a notable adverse financial and social effect upon patients’ life; for this, a good medicines adherence is demanded to achieve good daily activity and better quality of life.
AIM OF STUDY:
To explore adherence to medicines in Iraqi patients with Ankylosing spondylitis.
PATIENTS & METHODS:
A cross-sectional study enrolled 100 (96 males and 4 females) Iraqi patients with Ankylosing Spondylitis diagnosed according to ASAS criteria. Data collection was done using questionnaires and interview. Adherence quantified using Arabic version of 8-item Morisky Medication Adherence Scale (MMAS-8).
RESULTS:
High score of adherence to medicines in the study population was found, and the mean of the score was (6.8±1.6) with 83% of studied patients showing moderate to high adherence. A strong positive correlation found between the adherence & both the kind of treatment (Non-Steroidal Anti Inflammatory Drugs) and number of medicines taken.
CONCLUSION:
Most of the studied Ankylosing Spondylitis patients were adherent to their treatment.
BACKGROUND:
Ankylosing spondylitis is a chronic progressive inflammatory disease affecting spine and other joints leads to great disability and chronic pain, and has a notable adverse financial and social effect upon patients’ life; for this, a good medicines adherence is demanded to achieve good daily activity and better quality of life.
AIM OF STUDY:
To explore adherence to medicines in Iraqi patients with Ankylosing spondylitis.
PATIENTS & METHODS:
A cross-sectional study enrolled 100 (96 males and 4 females) Iraqi patients with Ankylosing Spondylitis diagnosed according to ASAS criteria. Data collection was done using questionnaires and interview. Adherence quantified using Arabic version of 8-item Morisky Medication Adherence Scale (MMAS-8).
RESULTS:
High score of adherence to medicines in the study population was found, and the mean of the score was (6.8±1.6) with 83% of studied patients showing moderate to high adherence. A strong positive correlation found between the adherence & both the kind of treatment (Non-Steroidal Anti Inflammatory Drugs) and number of medicines taken.
CONCLUSION:
Most of the studied Ankylosing Spondylitis patients were adherent to their treatment.
 
Keywords
BACKGROUND: Ankylosing spondylitis is a chronic progressive inflammatory disease affecting spine and other joints leads to great disability and chronic pain, and has a notable adverse financial and social effect upon patients’ life; for this, a good medicines adherence is demanded to achieve good daily activity and better quality of life. AIM OF STUDY: To explore adherence to medicines in Iraqi patients with Ankylosing spondylitis. PATIENTS & METHODS: A cross-sectional study enr
References
  1. Shahinyan A, Margaryan L, Samuel S. Ankylosing Spondylitis. In Pain Textbook 2019 :1239-41. Springer, Cham.
  2. Rudwaleit M, Khan MA, Sieper J. The challenge of diagnosis and classification in early ankylosing spondylitis: do we need new criteria?. Arthritis & Rheumatism. 2005;52:1000-8.
  3. Wenker KJ, Quint JM. Ankylosing spondylitis. [Internet] 2018 Nov 14. StatPearls Publishing.at https://europepmc.org/article/NBK/nbk470173
  4. Nasution AR, Mardjuadi A, Kunmartini S, etal. HLA-B27 subtypes positively and negatively associated with spondyloarthropathy. The Journal of rheumatology. 1997;24:1111-14.
  5. Dean LE, Jones GT, MacDonald AG, etal. Global prevalence of ankylosing spondylitis. Rheumatology. 2014;53:650-57.
  6. Al-bedri K. prevalence, clinical features, and radiological features of Iraqi patients with ankylosing spondylitis. JNSR. 2014;24:53-9.
  7. Brown MA, Kennedy LG, Macgregor AJ, etal. Susceptibility to ankylosing spondylitis in twins the role of genes, HLA, and the environment. Arthritis & Rheumatism. 1997;40:1823-28.
  8. Zhu W, He X, Cheng K, et al. Ankylosing spondylitis: etiology, pathogenesis, and treatments. Bone Res. 2019;7:1-6.
  9. Van der Linden SM, Khan MA, Rentsch HU, etal. Chest pain without radiographic sacroiliitis in relatives of patients with ankylosing spondylitis. The Journal of rheumatology. 1988;15:836.
  10. Rudwaleit M. New Classification Criteria for Spondyloarthritis. International Journal of Advances in Rheumatology. 2010;8.
  11. Van der Heijde D, Ramiro S, Landewé R, etal. 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis. Annals of the rheumatic diseases. 2017;76:978-91.
  12. Dagfinrud H, Hagen KB, Kvien TK. Physiotherapy interventions for ankylosing spondylitis. Cochrane Database of Systematic Reviews. 2008.
  13. Chen J, Veras MM, Liu C, Lin J. Methotrexate for ankylosing spondylitis. Cochrane database of systematic reviews. 2013.
  14. Chen J, Lin S, Liu C. Sulfasalazine for ankylosing spondylitis. Cochrane Database of Systematic Reviews. 2014.
  15. Dobbels F, Van Damme-Lombaert R, Vanhaecke J, De Geest S. Growing pains: non-adherence with the immunosuppressive regimen in adolescent transplant recipients. Pediatr Transplant 2005;9:381-90.
  16. Sabaté E, Sabaté E, editors. Adherence to long-term therapies: evidence for action. World Health Organization; 2003..
  17. Wabe N, Lee A, Wechalekar M, etal. Adherence to combination DMARD therapy and treatment outcomes in rheumatoid arthritis: a longitudinal study of new and existing DMARD users. Rheumatol Int 2017;37:897-904.
  18. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005;353:487-97.
  19. Smolen JS, Gladman D, McNeil HP, etal. Predicting adherence to therapy in rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis: a large cross-sectional study. RMD open. 2019;5.
  20. Hromadkova L, Soukup T, Vlcek J. Quality of life and drug compliance: their interrelationship in rheumatic patients. J Eval Clin Pract 2015;21:919-24.
  21. Ashur, S.T., Shamsuddin K, Shah SA, etal. Reliability and known-group validity of Arabic version of the 8-item Morisky Medication Adherence Scale among type 2 diabetes mellitus patients. Eastren Mediterranean Health Journal. 2015;21.
  22. Lavielle M, Puyraimond-Zemmour D, Romand X, etal. Methods to improve medication adherence in patients with chronic inflammatory rheumatic diseases: a systematic literature review. RMD open. 2018;4.
  23. Goh H, Kwan YH, Seah Y, etal. A systematic review of the barriers affecting medication adherence in patients with rheumatic diseases. Rheumatology International. 2017;37:1619-28.
  24. Tolu S, Rezvani A, Karacan İ, Bugdaycı D, Küçük HC, Bucak ÖF. Self-Reported Medication Adherence in Patients With Ankylosing Spondylitis: The Role of Illness Perception and Medication Beliefs. Arch Rheumatol 2020; 35 (x): i-xi. Arch Rheumatol ii occupational activities, resulting in considerable socioeconomic burden for patients and society. 2020;2:2.
  25. Michetti P, Weinman J, Mrowietz U, Smolen J, Peyrin-Biroulet L, Louis E, Schremmer D, Tundia N, Nurwakagari P, Selenko-Gebauer N. Impact of treatment-related beliefs on medication adherence in immune-mediated inflammatory diseases: results of the global ALIGN study. Advances in therapy. 2017;34:91-108.
 

 

Statistics
Article View: 31
PDF Download: 53


Journal Management System. Powered by ejournalplus.com