Synthesis ,Characterization and Identification of New Oxazepine,Oxazepane and Oxazinane Compounds from reaction of ٍ Some )Z)-2-((2-hydroxybenzylideneamino)methyl)-2-(hydroxymethyl)propane-1,3-diol Derivatives with some cycloanhydrides.

M.Al-Kubaisi, Hameed; F.Abdul-Gaffor, Khalid; F. Hammadi, Waleed

doi:10.37652/juaps.2009.15365

	Synthesis ,Characterization and Identification of New Oxazepine,Oxazepane and Oxazinane Compounds from reaction of ٍ Some )Z)-2-((2-hydroxybenzylideneamino)methyl)-2-(hydroxymethyl)propane-1,3-diol Derivatives with some cycloanhydrides.
Journal of University of Anbar for Pure Science
Article 10, Volume 3, Issue 2, August 2009, Pages 32-40 PDF (967.06 K)
Document Type: Research Paper
DOI: 10.37652/juaps.2009.15365
Authors
Hameed M.Al-Kubaisi¹; Khalid F.Abdul-Gaffor¹; Waleed F. Hammadi²
¹University of Anbar - College of Science
²University of Anbar - College of Education for women
Abstract
:- Z)-2- ((2-hydroxybenzylideneamino)methyl -2 -(hydroxy)propane -1,3-diol,)E) -4- (3-hydroxy-2,2-bis (hydroxyl methyl) propylimino)pentan-2-one, -2- ((4-(hydrazonopentane -2-ylideneamino methyl)-2 -(hydroxyl methyl)propane-1,3-diol and (Z)-2-((4-amino-1,5-dimethyl-2-phenyl-1H –pyrazol-3(2H)-ylideneamino)methyl)-2-(hydroxymethyl)propane-1,3-diol were prepared by condensation of 2-(aminomethyl)-2-(hydroxymethyl)propane-1,3-diol with 2-hydroxy benzaldehyde, pentane-2,4-dione, (E)-4-hydrazonopentan-2-one and 4-amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one .These Schiff- bases were reacted with Succinic, Maleic and Malonic anhydride in absolute ethanol to give 6,7-membered heterocyclic ring system Oxazepine,Oxazepane,Oxazinan.The Schiff-bases and the final products were identified by their melting points, elemental analysis, FT-IR and UV-Visible spectra.
Keywords
Schiffbases; oxazepine; oxazepane; Oxazinan Synthesis; properties; Identification Studies

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