Synthesis and Characterization of New Contact lenses Based on 2-Hydroxyethyl methacrylate | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 14, Issue 4, December 2014, Pages 72-96 PDF (0 K) | ||
| Author | ||
| Mohammed A. Mutar | ||
| Abstract | ||
| In this present work describes the synthesis new soft contact lenses based on 2-Hydroxy ethyl methacrylate monomer.2-Hydroxylethylmethacrylate (HEMA) was polymerized by free radical polymerization in the presence of ethylene glycol dimethacrylate (EGDMA) as acrosslinker and Benzoyl peroxide as initiator. The polymerized materials were characterized fully for its use fullness as an intraocular lens by various techniques. FTIR and 1HNMR were performed to find out the total conversion of monomer 2-Hydroxylethyl methacrylate into hydrogels contact lens. The hydrogels contact lenses were manufactured from different materials, these materials and water content were: copolymerization 2-Hydroxylethyl methacrylate with methacrylic acid (77.1%), Chitosan 82%, Methylacrylate 54%, Ethylhexyl methacrylate 56%.The equilibrium water content (EWC) was measured for all the hydrogels at 34°C and it was observed that the hydrophilic hydrogels swelling more than hydrophobic hydrogels. The oxygen permeability (DK) was measured by Morgan & Efron equation, the results show, the hydrophilic hydrogels display higher oxygen permeability towards the cornea more than hydrophobic hydrogels. The amount of proteins adsorbed on the membrane surface of hydrogels contact lenses was calculated from the concentration of proteins in the SDS solution using a BCA protein assay reagent kit. The results show albumin deposits in higher concentrations on hydrophobic surfaces, as compared to relatively hydrophilic surfaces.The transparency of all hydrogels were examined by using UV-visible spectrophotometer. The results show that all hydrogels contact lenses allowed range of light transmittance 58-94% ,at wave lengths between 400-700nm. Keywords:Hydrogels;Contact lenses;Protien adsorption ;Oxygen Permability | ||
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