Serum High-Sensitivity C-Reactive Protein and Endogenous Sex Hormones in Diabetic Men. | ||
| Jornal of Biotechnology Research Center | ||
| Article 1, Volume 10, Issue 1, June 2016, Pages 48-52 | ||
| Author | ||
| Shakir F.T. Al-Aaraji | ||
| Abstract | ||
| The objective of this cross sectional study was to assess the effect of diabetes mellitus (DM) type 2 in men on endogenous sex hormones: estradiol (E2) and total testosterone (TT); pituitary gland hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH) as well as high sensitive C-Reactive protein (hs-CRP) in men. This study comprised a total of (80) subjects out of which (40) were normal and (40) were diabetic males. The results obtained indicated a significant increasing (p≤ 0.05) of serum hs-CRP and E2 in men with DM type 2 comparison to non-diabetics, while a significant reduction (p≤ 0.05) of serum testosterone in men with DM type 2 comparison to non-diabetics, and non-significant reduction of serum LH, FSH in men with DM type 2 comparison to non-diabetics were observed. The data from this study show the role of endogenous sex hormones and hs-CRP in diabetes risk. Testosterone levels are partly influenced by insulin resistance, which may represent an important avenue for intervention. | ||
| Keywords | ||
| diabetes mellitus type; CRP; FSH; Testosterone | ||
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