Some Physiological Changes in Infantile Hyperbilirubinimia | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 11, Issue 4, December 2014, Pages 1037-1046 | ||
| Authors | ||
| Muhammad O. Al-Muhammadi; Mudher H.Al-Arajji; Jumana Sami Khudhair | ||
| Abstract | ||
| This study was designed to estimate some hematological and biochemical changes in hyperbilirubinic patients .The levels of these substances are very important in letting the health care team to know how the body is responding to the different therapies that being provided and this will help the medical staff for proper management . The study lasted from Desember/2009 to Jaune/2010. The patients are 106 with neonatal jaundice (65 males 41 females), and 84 controls are taken in this study (clinically assessed by specialist) .The patients (1day- <30days ) are classified into 4 subgroups: The first subgroup(A):- The blood group is similar between the mother and baby, The second subgroup(B):- the blood group is different between the mother and baby, The third subgroup(C):- the (RH) differences between the mother and baby and The fourth subgroup (D):- have G6PD deficiency. Those patients were admitted to the Babylon maternity and children teaching hospital .Concerning the hematological parameters, it is found that the hemoglobin (Hb) and packed cell volume (PCV) showed significant decrease (p<0.05) in subgroup C&D in comparison with controls. The white blood cells (WBCs) count showed no significant changes (p values>0.05) in comparison with controls (except the subgroup D) which showed significant increase in comparison with controls. The red blood cells count RBCs count showed no significant changes (p values>0.05) in all subgroups in comparison with controls. Regarding the biochemical parameters, the serum of total and indirect bilirubin showed significant increase (p <0.05) for all sub groups in comparison with controls. Regarding the serum Zinc and GSH which showed significant decrease of all values in comparison with controls , while the serum Copper showed significant increase for males and females of all age groups in comparison with controls, except the subgroup A which showed no significant changes in comparison with controls. | ||
| Keywords | ||
| hematological; Hyperbilirubinimia; Infantile | ||
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