Asymptomatic Thyroid Disorders In Type 1 Insulin Dependent Diabetes Mellites of Childhood | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 11, Issue 3, September 2014, Pages 606-612 | ||
| Author | ||
| Jasim Mohammed Hashim | ||
| Abstract | ||
| Objective: The type 1 insulin dependent diabetes mellitus (T1DM) and thyroid dysfunctions are common endocrine disorder and each condition affect the others, The associations between these two conditions are well documented, (T1DM) patients are prone to thyroid disorders for different causes . we aim in this study to evaluate thyroid disorder among children with T1DM . Methods : A hospital based case control study conducted in the clinic of endocrine disorders in Alzahra Teaching Hospital for the period between 1st of May 2012 to 31th of January 2013. Fifty patients with type 1 insulin dependent diabetes mellitus (T1 IDDM) consists of group A. The control group (group B)consist of Fifty healthy children . Serum level of TSH,T3,T4 were measured by using Minividas for both groups . Results: Patients aged 5-11 years, Boys were 27 and girls 23 .The mean age of patients was 7.2±1.53 years. The Mean concentrations of TSH were 4.05 ± 1.98 mlU/L in the patients with type 1 diabetic and this is significantly higher than the control group 2.29±0.87 mlU/L with Statistically significant difference (p <0.008). Whereas mean concentrations of TT3 were 1.82 ± 0.35mlU/L in group A and 2.16±0.43 mlU/L in group B this result is significantly lower than the control group with Statistically significant difference (p <0.01) .while there was no significant difference in TT4 values between the type 1 diabetic patients 103.38±8.4 mlU/L and control group 109.70±6.72 mlU/L with(p=0.15) Conclusion: This study shows Thyroid disorder is common in type 1 diabetic children. Periodic estimation of TSH and a lesser degree TT3 is important for early detection of thyroid disorder in T1DM patients before appearance of any clinical signs of thyroid disease. | ||
| Keywords | ||
| Thyroid disorder; Type | ||
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