Effect of phenolic compoundsof leaves extracts from Mentha longifolia and Mentha spicata on somebiochemical parameters of female rats | ||
| Journal of College of Education for Pure Science | ||
| Article 1, Volume 4, Issue 1, June 2014, Pages 309-315 | ||
| Authors | ||
| Khalid G. Al-Fartosi; Eman A. Al-Rekabi | ||
| Abstract | ||
| The objective of this study was performed toextract the phenolic compounds from Mentha longifoliaand Mentha spicata, and to shed a light on their activity against oxidant- antioxidant status and their effect on lipid profile in female rats. Two doses (200 and 400 mg/kg) from each plant were used and the animals were injected intraperitonially for 30 days as one dose/day. The results showed a significant decrease in the MDA and CP of the female rats treated with phenolic extracts of M. longifolia at dose (200-400) mg/kg and phenolic extracts of M. spicata at dose 200 mg/kg, and a significant decrease in the serum level of cholesterol and TG of the female rats treated with phenolic extracts ofM. longifolia at dose (200-400) mg/kg and phenolic extracts of M. spicata at dose 200 mg/kg, and The results showed a significant increase in the HDL and a significant decrease in the LDL with phenolic extracts of M. longifolia at dose (200-400) mg/kg when compared with control group, which treated with normal saline. While the female rats treated with phenolic extracts of M. longifolia and M. spicata at dose (200,400) mg/kg showed non significantdecrease in plasma VLDL, when compared with control group. | ||
| Keywords | ||
| Mentha spicata; Mentha longifolia; phenolic compounds; MDA; HDL; LDL; VLDL | ||
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