Evaluation of Certain Acute Phase Reactants in Patients with Acute Myocardial Infarction | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 13, Issue 2, June 2014, Pages 176-180 PDF (0 K) | ||
| Authors | ||
| Noaman Abdullateef Abdulrazzaq; Abdulbasit Insief Jassim; Ali Ibrahim Kadhum | ||
| Abstract | ||
| ABSTRACT: BACKGROUND : Acute myocardial infarction ( AMI ) is an important clinical condition which is associated with a significant inflammatory changes that result in acute-phase responses. Significantly elevated concentrations of cytokines and other acute phase reactants are the major events that accompanied such condition. Our aim was to evaluate certain acute phase reactants : Interleukin-6 ( IL-6 ) , C-Reactive Protein ( CRP ) and plasma fibrinogen in patients with AMI. OBJECTIVE: This study was focused on the evaluation of certain acute phase reactants : Interleukin-6 ( IL-6 ) , C-Reactive Protein ( CRP ) and plasma fibrinogen in patients with AMI. PATIENTS AND METHODS: Thirty patients from Baghdad city with AMI were included between July 2011 and January 2012 : 21 males and 9 females, their ages range between 40 – 73 years. Thirty healthy subjects ( 16 males, 14 females ), age matched with patients as a comparative group were included. Both groups were investigated for IL-6 , CRP , and plasma fibrinogen levels. RESULTS : IL-6 concentrations were found to be significantly higher with ( P value : 0.0001 ) –table 1- in patients with AMI) than in control subjects. CRP concentrations were also found to be significantly higher with ( P value : 0.0001 ) in patients with AMI than in control subjects. plasma fibrinogen level was significantly higher with ( P value : 0.0001 ) in patients with AMI than in control subjects. CONCLUSION : The study revealed a significant elevation in IL-6 , CRP concentrations and plasma fibrinogen level in patients with AMI. | ||
| Keywords | ||
| KEY WORDS; reactive protein; fibrinogen | ||
|
Statistics Article View: 162 PDF Download: 55 |
||