The Role of anti –DNA Abs. in Chronic Renal Failure in Diabetes Mellitus Type I and Type II | ||
Iraqi Postgraduate Medical Journal | ||
Article 1, Volume 13, Issue 2, June 2014, Pages 165-168 PDF (0 K) | ||
Authors | ||
Suha A.AL-Fakhar; Manal Kamal Rasheed; Mohammed Kamal Rasheed | ||
Abstract | ||
ABSTRACT: BACKGROUND: Diabetic nephropathy (DN) is the leading cause of CKD and end-stage renal disease (ESRD). CKD is characterized by a progressive loss of renal function, chronic inflammation OBJECTIVE: To compare the relationship between the anti –DNA Abs in diabetic patients type 1 and type 2 and their relation with chronic renal failure. METHODE: The ELISA methods was used to detect the presence of anti-DNA –Abs in sera of diabetic patients with type 1 and type 2 D.M. with CRF. RESULT: The concentration of anti-DNA Abs. were more in type II D.M. patients with CRF than those with type I D.M. without CRF and control group. CONCLUSION: The anti-DNA Abs. play an important role in the CRF in patients with long duration of D.M. type II ,while in patients with short duration of D.M. type I , anti-DNA Abs. do not play a role. | ||
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