Environmental Benign Synthesis, Characterization and Antimicrobial Activity of Some Imidazole Derivatives | ||
| Iraqi National Journal Of Chemistry | ||
| Article 1, Volume 0, Issue 54, November 2014, Pages 208-216 | ||
| Authors | ||
| V.K. Sharma; Dimple K. Rathore | ||
| Abstract | ||
| Abstract A series of imidazole derivatives by condensation of, differently substituted 4-benzylidene-2-phenyloxazol-5(4H)-one and 2-aminothiazole, which on further reaction with Urea and Thiourea produces the final products(substituted 8-phenyl-9-(thiazol-2-yl)-6,9-dihydro-1H-purin-2(3H)-one 3(a-f) and substituted 8-phenyl-9-(thiazol-2-yl)-6,9-dihydro-1H-purine-2(3H)-thione 4(a-f)). IR, H1 NMR and MASS spectral data confirmed the structure of the newly synthesized compounds. All the reactions were carried out by environmental benign, efficient and extremely fast procedure Microwave synthesis. The derivatives of these moieties were evaluated for antimicrobial activity. | ||
| Keywords | ||
| Microwave assisted synthesis; imidazole; purine; antibacterial activity; Antifungal activity | ||
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