The effect of zinc and selenium on blood pictures and concentration of some hormones in albino male rats exposed to oxidative stress. | ||
| Journal of Tikrit University For Agriculture Sciences | ||
| Article 1, Volume 14, Issue 1, June 2014, Pages 270-278 | ||
| Authors | ||
| SuhaHussin Mohammed AL-Mashhadany; Saheb J. Abdoul-Rahman | ||
| Abstract | ||
| The study aimed to investigate some effects of the zinc and selenium on some blood picture (Hb, Pcv and WBCs) and the concentrations of Testosterone hormone (testo.), Luteinizing Hormone (LH), Prolactin (PRL) in the male rates testo exposed to oxidative stress induced by hydrogen peroxide. The study included (40) male albino rats,(3-4) months ages and (245-280) gm weight were divided to (8) groups both group with (5) rats as follows:Control group, hydrogen peroxide (H2O2) 1% group, zinc(100 mg Zn/Kg of food)+ H2O2 (1%) group,selenium(100 μg Se/Kg of food)+ H2O21% group, zinc (100mg) and selenium(100 g)+ H2O2(1%)group, zinc group(100 mg Zn/Kg of food), selenium group(100 μg Se/Kg of food) and zinc(100mg) and selenium(100 μg) together group.The results showed a significant decrease(p≤ 4.45) in the concentration of (testo), (LH) and the values of Hb , PCV in the group exposed to oxidative stress induced by hydrogen peroxide compared with the control group. The WBCs showed significant increase in the group exposed to oxidative stress induced by hydrogen peroxide compared with the control group While non significant differences showed in the concentration of prolactin hormone in the study group.The groups exposed to oxidative stress and treatment with zinc, selenium and zinc,selenium together showed significant increase in the in concentration of testo, LH, Hb, and PCV, significant decrease in WBCs when compared with a hydrogen peroxide group.The group treatment zinc and selenium shwed significant increase in value Hb, While non significant differences showed in the concentration of Tsto, LH, PCV and WBCs when compared with control group.The treatment of animals by zinc and selenium together showed significant increase in the in concentration of Testototo, LH and Hb, While non showed significant differences in the values of PCV, WBCs when compared with control group. | ||
| Keywords | ||
| antioxidant; albino; stress | ||
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