Effect of Gumboro D78 vaccine on some lymphoid organs in domesticated fowls (Gallus gallus domesticus). | ||
| Journal of Tikrit University For Agriculture Sciences | ||
| Article 1, Volume 14, Issue 1, June 2014, Pages 262-269 | ||
| Author | ||
| A. Ul-Jabbar M. H. Aljoburi | ||
| Abstract | ||
| This study was done in animal house of the Veternary Medicine / University of Tikrit from 20 / 3 / 2013 to 16 / 4 / 2013 to determine the gross and histological changes in domesticated fowls vaccinated with Gumboro vaccine (D 78) by eye drops at one day. Samples of spleen, thymus and bursa of Fabricius were taken at age 4 , 7, 14, 21, 28 days post vaccination. Results indicate, gross changes were characterized by atrophy of thymus and congestion, congestion of spleen, with showed presence of gelatinous material in bursa of Fabricius in some samples. Histologically, the thymus showed disappearance parts of the cortex at age 4 days old. Also showed present hyperplasia around the splenic artery at 21 days old post vaccination, in addition to their showed lymphocytes aggregation in the nodes at 28 days old . The bursa of Fabricius showed follicular atrophy with perifollicular hemorrhagic on days 4 and 7 post vaccination, whereas showed intrafollicular lymphatic necrosis with severe degenerations in follicles on days 14 , 21 , 28 post vaccination . This study concludes that Gumboro vaccine, where it led to appearance atrophy and congestion on some lymphoid organs with intrafollicular lymphatic necrosis and severe degenerations in vaccinated domesticated fowls. | ||
| Keywords | ||
| Gumboro D; Vaccine; fowls | ||
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