Bioactivity of of ethylacetat extract of green alga Cladophora crispate against Entamoeba histolytica and Giardia lamblia parasites compared with Metronidazole (Flagyl) drug in vivo | ||
| Journal of Basrah Researches (Sciences) | ||
| Article 1, Volume 40, Issue 2, September 2014, Pages 91-103 PDF (0 K) | ||
| Authors | ||
| H. Al- Mayah; ; ; ; M. Athbi and Dalal | ||
| Abstract | ||
| The present study included testing the biological activity of ethylacetat extract of green algae Cladophora crispate against Entamoeba histolytica and Giardia lamblia parasites at concentrations( 0.10, 0.15 ,0.2, 0.25mg / ml) compared with the metronidazole (Flagyl) drug at concentration (30 mg / ml) in laboratory mice Mus musculus strain Balb / c, the results showed that Hexadecanoic acid ethyl ester and Phytol and Hexatriacontan compounds which isolated and diagnosed in the extract by gas chromatography - mass spectrometry ( GC-Mass) technology are effective against these parasites , E.histolytica parasite was eliminated in the sixteenth day at 0.25 mg / ml of extract compared with Flagyl drug which eliminated this parasite in the seventeenth day , while G.lamblia parasite was eliminated in the sixteenth day at 0,2 mg / ml of extract compared with Flagyl drug which is eliminated this parasite in the sixteenth day , and the results showed that the therapeutic efficacy of extract and Flagyl drug are close to each other , the therapeutic efficacy of extract and drug against E.histolytica was ( 76.93 % and 80.41 % , respectively) , while the therapeutic efficacy of extract and drug against G.lamblia was ( 81.85 % and 83.34 % , respectively). | ||
| Keywords | ||
| Cladophora crispate; Entamoeba histolytica | ||
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