Synthesis and characterization of some new bis 1,3-oxazepines and 1,3-imidazolidine with evaluating of its biological activity. | ||
| karbala journal of pharmaceutical sciences | ||
| Article 1, Volume 5, Issue 7, June 2014, Pages 108-122 PDF (0 K) | ||
| Authors | ||
| Fawzi Hameed Jumaa and; Rashed Fadel Abbass | ||
| Abstract | ||
| In this study some new compounds have been synthesized including preparation of some different Schiff bases (1-5) from the reaction of aromatic amines with terphthadehyde in absolute ethanol and converted into derivatives of 1,3-Oxazepine (of ring closure reaction (2 +5) of Schiff bases with maleic anhydride in benzene (6-10) besides the 1,3- Imidazolidenon (11-15) and evaluation of biological activity for some of them. The prepared compounds were characterized by FT-IR spectra and 1H-NMR spectra for some of the prepared compounds besides the determination of their melting points and TLC (Thin Layer Chromatography. | ||
| Keywords | ||
| Schiff bases; Oxazepines; imidazolidinone | ||
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