Synthesis and Biological testing of new 1,3- oxazepine derivatives of pharmaceutical interest | ||
karbala journal of pharmaceutical sciences | ||
Article 1, Volume 5, Issue 7, June 2014, Pages 21-30 PDF (0 K) | ||
Authors | ||
Khalid.M .Mohamad Al-janaby; | ||
Abstract | ||
Some derivatives of 1,3 oxazepine – Schiff bases have been synthesized by the reaction of some aromatic aldehydes with N-phenyl azo aniline to synthesis of the compounds ,2-(p-phenyl azo)-1,4-phenylene aniline(1-6) ,and these compounds (1-6) were reacted with phthalic anhydride to obtain derivatives of 1,3- oxazapine. The chemical structures of the products were characterized by (IR ,and 1H NMR) and biological activity for some of these compounds were studied against three kinds of bacteria | ||
Keywords | ||
synthesis; Schiff bases; oxazepine; biological teste | ||
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