Comparative Study Between The Clinical Effects of Glucosamine/Gingko Biloba & Glucosamine/Chondroitin in Treatment of Knee Osteoarthritis | ||
| kufa Journal for Nursing sciences | ||
| Article 1, Volume 4, Issue 2, August 2014, Pages 167-174 | ||
| Author | ||
| Mohammed Dakhil Al-Rekabi | ||
| Abstract | ||
| Aim: This study was designed to investigate the effect of two widely used combinations, glucosamine/chondroitin and glucosamine/ginkgo biloba on the clinical picture of patient with osteoarthritis(OA). Methods: Fifty one (51) osteoarthritis patients ( 21 male and 30 female) were participated in this research depending on certain selection criteria. The selected patient were randomly allocated into two groups: group A includes 22 ( 9 male and 13 female) patients treated with a combination of glucosamine /gingko biloba ( 500/ 50 mg twice daily ) for six weeks whereas group B includes 29 (12 male and 17 female) patients treated with a combination of glucosamine/chondroitin (500/ 400mg twice daily ) for six weeks . Effects of drug treatment were assessed each seven days by clinical evaluation and direct interview with patients through a questionnaire method known as Knee Injury and Osteoarthritis Outcome Score (KOOS). Results: It was found that all components of KOOS including pain score, symptoms score, activity of daily living (ADL), quality of life (QOL) and sport & recreation scores were significantly elevated (improved) in both combinations, however, glucosamine /gingko biloba showed a better improvement when statistically compared with the combination of glucosamine/chondroitin. Conclusions: It is concluded from this study that the glucosamine sulfate is more clinically useful for OA when combined with gingko biloba than when it is combined with chondroitin. Recommendations: A large scale cohort study is recommended to ensure the clinical findings. | ||
| Keywords | ||
| Osteoarthritis; Glucosamine sulfate; Chondroitin sulfate; Gingko biloba; Knee joint and osteoarthritis outcome score | ||
|
Statistics Article View: 109 PDF Download: 41 |
||