A. Haroun, M., Salim Al-shehmany, A., M.Embaby, A., A. El-Kafoury, A. (2014). Contribution of IL-10 (SNP -819 C/T and SNP-1082 G/A) polymorphisms variants to the risk of type 1 diabetes in Egyptian population. Alustath, 13(1), 54-60.
Medhat A. Haroun; Ali Salim Al-shehmany; Amira M.Embaby; Ahmad A. El-Kafoury. "Contribution of IL-10 (SNP -819 C/T and SNP-1082 G/A) polymorphisms variants to the risk of type 1 diabetes in Egyptian population". Alustath, 13, 1, 2014, 54-60.
A. Haroun, M., Salim Al-shehmany, A., M.Embaby, A., A. El-Kafoury, A. (2014). 'Contribution of IL-10 (SNP -819 C/T and SNP-1082 G/A) polymorphisms variants to the risk of type 1 diabetes in Egyptian population', Alustath, 13(1), pp. 54-60.
A. Haroun, M., Salim Al-shehmany, A., M.Embaby, A., A. El-Kafoury, A. Contribution of IL-10 (SNP -819 C/T and SNP-1082 G/A) polymorphisms variants to the risk of type 1 diabetes in Egyptian population. Alustath, 2014; 13(1): 54-60.

Contribution of IL-10 (SNP -819 C/T and SNP-1082 G/A) polymorphisms variants to the risk of type 1 diabetes in Egyptian population

Iraqi Journal of Biotechnology
Article 1, Volume 13, Issue 1, April 2014, Pages 54-60
Authors
Medhat A. Haroun; Ali Salim Al-shehmany; Amira M.Embaby; Ahmad A. El-Kafoury
Abstract
This study investigated whether interleukin- 10 (IL-10) gene promoter region polymorphisms are associated with susceptibility or clinical presentation of type 1 diabetes. The frequency of -1082G/A and -819C/T, polymorphisms was analyzed in 60 Egyptian patients with type 1 diabetes and in 60 healthy control subjects in a case-controlled study. However, the -819C/T not showed significance between patient and control (P=0.208) and 1082G/A were associated with T1DM disease (P<0.0001). These results suggest that the IL-10 gene promoter polymorphisms are associated with type 1 diabetes in Egyptian population.
Keywords
Interleukin; polymorphisms; Type
Statistics
Article View: 42
PDF Download: 12


Journal Management System. Powered by ejournalplus.com