Lafta Abdul Hassan, M., Hussein Moyet AL-Faisal, A. (2014). Apoptosis and Necrosis Levels in Chemotherapy Treated Chronic Lymphocytic Leukemia Patients. Alustath, 13(1), 39-45.
Manal Lafta Abdul Hassan; Abdul Hussein Moyet AL-Faisal. "Apoptosis and Necrosis Levels in Chemotherapy Treated Chronic Lymphocytic Leukemia Patients". Alustath, 13, 1, 2014, 39-45.
Lafta Abdul Hassan, M., Hussein Moyet AL-Faisal, A. (2014). 'Apoptosis and Necrosis Levels in Chemotherapy Treated Chronic Lymphocytic Leukemia Patients', Alustath, 13(1), pp. 39-45.
Lafta Abdul Hassan, M., Hussein Moyet AL-Faisal, A. Apoptosis and Necrosis Levels in Chemotherapy Treated Chronic Lymphocytic Leukemia Patients. Alustath, 2014; 13(1): 39-45.

Apoptosis and Necrosis Levels in Chemotherapy Treated Chronic Lymphocytic Leukemia Patients

Iraqi Journal of Biotechnology
Article 1, Volume 13, Issue 1, April 2014, Pages 39-45
Authors
Manal Lafta Abdul Hassan; Abdul Hussein Moyet AL-Faisal
Abstract
The results showed that CLL patients chemotherapy treatment increase the expression of Bcl2 gene (via measuring the phosphatidylserine -PS level) which increased apoptosis and necrosis percentage. It is also showed that the Necrotic cells (%) were found to be significantly higher in patients samples (1.07 ± 0.03) than in healthy (0.17 ± 0.02) with no significance in viable cells (%) (82.88% in patients and 86.8% in healthy). The apoptotic cells % were found to be significantly higher in patients (15.04 ± 1.03) than healthy (4.40 ± 0.5). On the other hand, late apoptosis % showed no significant results (0.639 % in patients and 0.803 % in healthy).
Keywords
CLL; Apoptosis; Bcl; Mutations; PCR
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