Effect of Cymbopogon citratus water extract in level of glutathione , liver activity ,the cellular and tissues changes in local rabbits treated with hydrogen peroxide and Alcohol. | ||
| Journal of Tikrit University For Agriculture Sciences | ||
| Article 1, Volume 14, Issue 1, June 2014, Pages 19-34 | ||
| Authors | ||
| QUSSAY NOORI RADDAM; ZAID MUHAMMAD MOBARK; SALEH MUHAMMAD RAHEEM | ||
| Abstract | ||
| This study was conducted to investigate the effect of Cymbopogon citrates extract to determined its ability in preventing oxidative stress of Hydrogen peroxide 2% and Al Cohol 20% consumed in drinking water by daily couple dose for 60 days in local rabbit with deferent protective effect against aging.Hydrogen peroxide 2% and Alcohol 20% treated showed significant decrease in Glutathione(GSH) and high significant increase in Malonaldehyde MDA and Peroxinitrite (Pn), also the levels of serum AST and ALT were significantly increase . these changes indicate to the ability of H2O2 2% and Alcohol 20% in the induction of oxidative stress in local rabbits. As well as the appearance pathological changes in liver tissue with the treatment with H2O2 and Al cohol. Histological examination showed Lipid changes of degeneration, Necrosis, Karyolysis and Vaceulation in the cytoplasm of hepatic cells. The treatment with water extract of Cymbopogon citrates showing significant increase in GSH and significant decrease in MDA, AST and ALT also showing improving of liver tissue and decrease in liver fat . | ||
| Keywords | ||
| water extract; Rabbits | ||
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