Preoperative Alterations of Interleukin-6 levels During Surgical Removal of Impacted Lower Third Molar | ||
| Al-Rafidain Dental Journal | ||
| Article 10, Volume 14, Issue 1, June 2014, Pages 76-81 PDF (0 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rden.2014.89256 | ||
| Authors | ||
| Harith D Qadawi; Atalla F. Rejab; Mahmoud YM Taha | ||
| Abstract | ||
| The aim of the study is to assess the blood levels of (interleukin-6) at different intervals of time after surgical removal of impacted lower third molars.. Materials and Methods: The study group comprised 26 patients with impacted lower third molars .All extractions were performed under local anaesthesia using the inferior alveolar nerve block together with vestibular infiltration. A buccal full thickness two sided mucoperiosteal flap was raised. Sterile low-speed straight hand pieces and sterile distilled water were used for ostectomy. After tooth removal the wound was closed with 3-0 black silk suture. Three blood samples were drawn from each patient; one before the operation, the second 2hr. post operation and the third 24hr. post operation. The blood samples were collected through venipunc-ture, serum separated and stored in at -20ºC. Analysis was performed using the Enzyme linked Im-munosourbant assay ( ELISA). Results: The level of IL-6, in this study, showed an increase following surgery, in comparison with the level before operation. This increase in the level of Interleukin-6 re-mained high until 24hr after operation. Conclusion: Interleukin-6 (IL-6) is higher after surgical extrac-tion of lower third molars and remained with high levels to 24hr. after operation | ||
| Keywords | ||
| Third molar surgery; cytokines; Interleukin | ||
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