Biological activity of 4-(2-methoxy benzylidene amino) phenyl mercuric chloride and 4-(2-chlorobenzylidene amino) phenyl mercuric chloride compounds | ||
| basrah journal of science | ||
| Article 1, Volume 32, Issue 1, September 2014, Pages 63-75 PDF (0 K) | ||
| Author | ||
| Eiman A. Saeed | ||
| Abstract | ||
| The 4-(2-methoxy benzylidene amino) phenyl mercuric chloride and 4-(2-chlorobenzylidene amino) phenyl mercuric chloride were investigated for their biological activity against standard strains of Staphylococcus aureus ATCC 25923 and Ecsherichia coli ATCC 25922. The results showed that there is a potent antibacterial activity of these compounds. Minimal inhibitory concentration was determined for these two compounds, it was 4 μg/ml, 5 μg/ml for Staph. aureus, and 15 μg/ml, 20 μg/ml for E. coli respectively. Cytotoxicity assay was carried out against human red blood corpuscles, the two compounds exhibited a toxic effect in high concentrations on RBCs while in high diluted concentrations have no toxic effect on it. | ||
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