EFFECT OF SELENIUM AND ZINC IN SOME OF IMMUNOLOGICAL CHARACTERS OF IRAQ EWES | ||
| Journal of University of Anbar for Pure Science | ||
| Article 4, Volume 7, Issue 2, August 2013, Pages 1-10 PDF (743.36 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2013.84868 | ||
| Authors | ||
| HASAN ALI MUTAR* 1; AUDAI SABAH ASKAR2; SULEEM OBAID ALMAWLA3 | ||
| 1Presidency of the University of Anbar-Central Laboratory | ||
| 2Presidency of Anbar University - Central Laboratory | ||
| 3Ministry of Health - Anbar Health Department | ||
| Abstract | ||
| This study has been done to know the effect of tow minerals zinc and selenium on the immunity through measurement of adenosine deaminase, globulin, total protein and albumin. In addition to know the effect of selenium and zinc on CBP (complete blood picture), biochemical blood characteristic, We used 25 Iraqi ewes with age ranging between 2-4 years and with average life body weight 40kg for period from February/ 2010 to September/2010,in farm of agriculture college – University of Anbar > This 25 ewes has been divided randomly into five groups (5 ewes for each group), first group given distilled water and considered as control group, 0.8 mg selenium given for second group and 1.6 mg for third group while 3.2 mg zinc given for fourth group and 6.4mg for last group. Oral supplement with these minerals has been continuing for 2 months, There are no significant differences between the groups treated with cholesterol and that treated with distilled water , the effects of the zinc and selenium on total protein and globulin level, (Zn1) group have highest level from others. But for albumin level there was no significant difference between control and treated groups.the two groups (Se1 and Zn1) have the best effect on CBP, as (Zn1) has higher number of RBC, lymphocytes, monocytes and granulocytes. While (Se1) group has higher number of lymphocytes and monocytes. In addition to that, these two groups have the best result for the Hb (hemoglobin), hematocrits and others. | ||
| References | ||
|
Ammerman, C. B.; D. H. Baker and A. J. Lewis(1995). Bioavailability of nutrients for animals (amino acids, minerals and vitamins). United Kingdom, Academic Press Limited. 24-28 Oval road, London, NW1 7DX.
2:-الدلیمی، حسن علی مطر. 2004. دراسة تأثیر السیلینیوم والزنک فی بعض الجوانب المناعیة والنسیجیة فی خنازیر غینیا. أطروحة دکتوراه–کلیة العلوم–جامعة الأنبار. 3:-Darlow, B. A. and N. C. Austin( 2007). Selenium supplementation to prevent short-term morbidity in preterm neonates: A review The Cochrane collaboration published in the Cochrane Library. 2007. Issue. Wiley Publishers Since 1807.
4:-Davis, P. A.; L. R. MCDowell; N. S. Wilkinson; C. D. Buergelt; R. V. Alstyne; R. N. Weldon; T. T. Marshall and E. Y. Fugisaki( 2008). Comparative effects of various dietary levels of Se as sodium selenite or Se yeast on blood, wool, and tissue Se concentrations of weather in sheep. J. Small Rum. Res. 74:149-158.
5:-Kuo, H. W.; S. F. Chen; C. C. Wu; D. R. Chen and J. H. Lee( 2002). Serum and tissue trace elements in patients with breast cancer in Taiwan. J. Biol. Trace Elem. Res. 89:1-11.
6:-Meplan, C. 2011. Trace elements and ageing a genomic perspective using selenium as an example. J. Trace Elem. in Med. and Biol. (2011) Article in press.
7:-Ucar, S. K.; M. Coker; E. Sozmen; D. G. Simsek and S. Darcan( 2010). An association among iron, cooper, zinc and selenium and antioxidative status in dyslipidemic pediatric patients with glycogen storage disease type IV and 144. J. Tra. Elem. In Med. And Biol. 24:42-45.
8:-Klotz, L. O.; K. D. Kronke; D. P. Buckczyk and H. Sies( 2003). Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and introsative stress. J. Nut. 133:1448s-1451s.
9:-Ramakrishnan, K. S. P. Sharma; R. Shenbagarathai; K. Kavitha and P. Thirumalaikolundu subramanian(2009). Serum selenium levels in pulmonary tuberculosis levels with and without HIV / AIDS. J. Bio. Med. Central. 2009. 9 (suppl2):p76, doi:10. 1186/1742-4690-6-S2, PT6.
10:-Sargison, N. D. and P. R. Scott(2010). The implementation and value of diagnostic procedures in sheep health management. J. Small Rum. Res. 92:2-9
11:-Rock, M. J.; R. L. Kincaid and G. E. Carstens(2001). Effects of prenatal source level of dietary selenium on passive immunity and thermometabolism of newborn lambs. J. Small Rum. Res. 40:129-138.
12:-Venupal, B. and T. D. Lucey(1978). Metal toxicity in mammals, 2chemical toxicity of metals and metallolds. Plenum press New York and London.
13:-Bozalioglu, S.; Y. Özkan; M. Turan and B. Simsek(2005). Prevalence of zinc deficiency and immune response in short-term hemodialysis. J. Trace Elem. in Med. and Biol. 18:243-249.
14:-Goswami, T. K.; R. Bhar; S. E. Jadhar; S. N. Joardar and G. C. Ram(2005). Role of dietary zinc as a nutritional immunomodulator. Asian-Aust. J. Anim. Sci. 18:439-452.
15:-Wellingheussen, N.; M. Martin and L. Rink(1997). Zinc inhibit interleukine-1dependent T-cell stimulation. Eu. J. Immun. 27:2529-2535.
16:-Guyot, H.; C. Saegerman; P. Lebreton; C. Sendersen and F. Rollin(2009). Epidemiology of trace elements deficiencies in Belgian beef and dairy cattle herds. J. Tra. Elem. In Med. And Biol. 23:116-123.
17:-Tomlinson, D. J.; M. T. Socha and J. M. Defrain(2007). Cow immunity boosted with trace minerals. J. Feed Tech. Magazine. Vol. 11. No. 10. www.allaboutfeed.net.
18:-Giusti, G. 1981. Adenosine deaminase. In methods of enzyme analysis. 2nd ed. by: Bergmeyar H. V. Academic press. pp. 1022-1099.
19:-Maff(1984). Ministry of agriculture fisheries and food: Manual of veterinary investigation techniques, Vol. 2. Reference book. 390. 3rd ed. by Davies, E. T.; J. A. Benson; S. R. Bicknel; D. E. Grey; S. G. Hewitt; J. R. A. Lloyd, Morrison; D. C. Ostler; G. A. Pepiin and C. M. Purvis. MAFF/ADASS.
20:-Kind, P. R. N. and E. G. King(1954). Estimation of plasma phosphate by determination of hydrolyzed phenol with aminoantipyrine. J. Clin. Path. 7:322-326.
21:-SAS, 2004. SAS User's guide: statistical system, Inc. Cary, NC. USA.
22:-Hefnawy, A. E. and J. L. T. Perez(2010). The importance of selenium and the effect of its deficiency in animal health. J. Smal. Rum. Res. 89:185-192.
23:-Gonzalez-Perez, J. M.; E. Gonzalez-Reimers; M. D. Duran-Castellon; F. Santolaria-Fernandez; L. Galindo-Martin; R. Rosvilamajo; M. Vega-Prieto; J. Rodriguez and P. Gonzalez(2011). Relative and combined effects of selenium, protein deficiency and ethanol on bone. J. Trace Elem. in Med. and Biol. Article in press.
24:-Sanchez, C.; M. Lopez-Jurado; E. Planells; J. Liopis and P. Arando(2009). Assessment of iron and zinc intake and related biochemical parameters in an adult Mediterranean population from South Spain: influence of lifestyle factors. J. Nutritional Biochemistry. 20:125-131.
25:-Kyriakopoulos, A.; D. Rothlein; H. Pfeifer; H. Bertlsmann; S. Kappler and D. Behne(2000). Detection of small selenium-containing proteins in tissues of the rat. J. Trace Elem. in Med. and Biol. 14:179-183.
26:-Diaz-Castro, J.; M. L. Ojeda; M. J. Alferez; I. Lopez-Aliaga; T. Nestares and M. Campos(2011). Se bioavailability and glutathione peroxidase activity in iron deficient rats. J. Trace Elem. in Med. and Biol. (2011) Article in press
27:-Zachara, B. A.; A. Adamowicz; U. Trafikowska; A. Trafikowska; J. Manitius and Z. E. Nartowic(2001. A). Selenium, glutathione levels and glutathione peroxidase activities in blood components of uremic patients on hemodialysis supplemented with selenium and treated with erythropoietin. J. Trace Elem. in Med. and Biol. 15:201-208.
28:-Bicek, K.; Y. Deger and S. Deger(2005). Enzyme activities in fascioliosis of cattle. J. Indian Vet. 82:803-804.
29:-Yuan, W.; X. Yu; F. Liu; H. Wang; D. Wang and X. Lai(2010). Effects of trace element supplementation on the inflammatory response in rabbit model of major trauma. J. Trace Elem. in Med. and Biol. 24:36-41.
30:-Haenlein, G. F. W. and M. Anke(2011). Minerals and trace element research in goats: A review. J. Small Rum. Res. Article in press. | ||
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