ANTICOAGULANT EFFECTS OF EMINIUM SPICULATUM AQUEOUS LEAF EXTRACT IN RABBITS | ||
| Basrah Journal of Veterinary Research | ||
| Article 1, Volume 12, Issue 2, December 2013, Pages 332-337 PDF (0 K) | ||
| DOI: 10.33762/bvetr.2013.83828 | ||
| Author | ||
| M. I. Al-Farwachi and B.A. AL- Badranii | ||
| Abstract | ||
| The effect of different doses of Eminium spiculatum aqueous leaf extract on coagulation of blood in the rabbits were studied .Animals treated with extract at a dose of 200 , and 400 mg / kg body weight intraperitoneally daily for 7 days produced a significant ( p < 0.05 ) increase in the clotting time , prothrombin time and activated partial thromboplastin time with normal platelet counts when compared with phosphate buffer saline ( untreated ) and heparin ( treated ) control rabbits. The effect of the extract on coagulation of the blood was shown to be dose – dependent . Result of this study suggest that extract shows considerable anticoagulant activity in rabbits and has potential to reduce cardiovascular morbidity and mortality. | ||
| Keywords | ||
| Anticoagulant effects; Poisonous plant; Rabbits | ||
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