Influence of hot alcohol extraction of Celery fruits on renal stones dissolution in vitro. | ||
| Jornal of Biotechnology Research Center | ||
| Article 1, Volume 8, Issue 1, March 2014, Pages 71-76 | ||
| Authors | ||
| Duha B. Mohamed; Saad H. Khudier; Nibal Kh. Mousa; Shahad Sh Sabbar | ||
| Abstract | ||
| This study was carried out to investigate the effect of hot alcohol extraction activity of Apium graveolens fruits on the common Renal stones dissolution (Ca-OX ,Uric acid) kinds and volatile oils concentrations on Apium graveolens via HPLC were estimated. Fourteen compounds which were (α-pinene, Cineole, P- cymene, Terpinene, α- phellandrene, β-pinene, Geraneole, α-terpinole, Linalool, Menthone, Limonene, Myrcene, Camphen, Rutin) were measured. In regard to concentration, α -pinene has the highest concentration since it reaches 19.2 µg/ml, while the lower concentration was achieved with Camphen which was 6.3 µg/ml. Results of Ca-Ox renal stones treated with extract of Apium graveolens showed significant decrease in stone weight since highest weight decrease percentage, using the hot alcoholic extract reaches 17.02 % at 5 % concentration and in comparison with Rowantinex drug, the results showed a high similitude between the hot alcoholic extract at 5% concentration and Rowantinex drug in respect of percentage of renal stones dissolution, so hot alcohol extraction of apium gravedens in 5% concentration was the best and active in dissolution Ca-OX at first degree and uric acid at second degree. | ||
| Keywords | ||
| hot alcohol extraction; Celery fruits; Renal stones | ||
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