Nosocomial outbreak of carbapenem-resistant Pseudomonas aeruginosa producing metallo beta lactamase in Al-Hilla teaching hospital, Babylon | ||
| Journal of University of Babylon | ||
| Article 1, Volume 22, Issue 1, January 2014, Pages 317-323 | ||
| Authors | ||
| Eman M. Jarallah; Mustafa J. Alammary | ||
| Abstract | ||
| Metallo-beta-lactamase MBL producing Pseudomonas aeruginosa have been reported to show resistance to carbepenem drugs. Detection of metallo-beta-lactamases producing P. aeruginosa is now important to prevent their spread as dissemination of these bacteria could be fatal to the patients. The present study was undertaken over period of six months from December-2011 to May-2012 in Al-hilla teaching hospital, to study the incidence of outbreak of MBL producing P.aeruginosa from various clinical specimens. Out of 247 clinical specimens 81 isolates were obtained . These isolates were subjected to susceptibility testing to antipseudomonal drugs as per CLSI guidelines, 32(40%) of isolates were carbapenem resistant P. aeruginosa (CRPA). They were further screened for production of MBL: by EDTA-imipenem synergy method and Carbapenemase production: by modified Hodge test and using E. coli ATCC 25922 for control. All (CRPA) isolates were MBL producing isolates and carbapenemase producing isolates. | ||
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