Synthesis, Structural Study, Antimicrobial Activity and Theoretical Treatment of 3d-metal Complexes Involving Schiff Base of Piperonal Derivative | ||
| Al-Mustansiriyah Journal for Pharmaceutical Sciences | ||
| Article 1, Volume 13, Issue 1, June 2013, Pages 1-13 | ||
| Authors | ||
| Israa Qais Yousif; Mahasin Faisal Alias | ||
| Abstract | ||
| Abstract: New VO (II), Cr (II), Co (II), Ni (II), Cu (II) and Zn (II) Schiff base complexes derived from piperonal have been synthesized and characterized by spectroscopic methods, conductivity, metal analyses and magnetic moment measurements. The nature of the complexes formed in ethanolic solution was study following the molar ratio method. From the spectral studies, Octahedral geometry was suggested for all prepared complexes except Vanadium (IV) and zinc (II) complexes have square pyramidal and tetrahedral geometry respectively, Structural geometries of these compounds were also suggested in gas phase by using hyper chem-8 program for the molecular mechanics and semi-empirical calculations. The heat of formation and binding energy for the prepared compounds was calculated by using PM3 and ZINDO/1 methods. The method of PM3 was used for evaluate the vibration spectra for the imine and starting material as authentic compound. Preliminary in vitro tests for antibacterial and antifungal activity show that most of the prepared compounds display good activity to (Staphylococcus aureus), (Escherichia coli) and (Candida albicans) Keywords: Schiff base, Piperonal, hyper chem-8, in vitro, Activity. | ||
| Keywords | ||
| KEYWORDS; Piperonal; hyper chem; In Vitro; activity | ||
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