Possible role of some aspects of immune response in aborted women infected with Toxoplasma gondii | ||
| Journal of University of Babylon | ||
| Article 1, Volume 20, Issue 3, August 2012, Pages 985-966 | ||
| Author | ||
| Jasim Hameed Taher | ||
| Abstract | ||
| The immune response that was induced by Toxoplasma gondii infection was found to be protective to mother, but it was deleterious to the fetus; i. e. the infection induced an immunopathological state in the fetus. The induction of high levels of TNF – α , IFN – , IL - 1α , IL – 6 , IL – 8 and IL – 10 due to T. gondii infection may exert an inhibitory effect on serodiagnosis (inhibition the synthesis of progesterone and estradiol) which may explain their possible role in termination of pregnancy. The mechanisms of the other factors may be also induced after T. gondii infection. | ||
| Keywords | ||
| Immune Response; gondii; abortion; progesterone and estradiol | ||
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