Testosterone level and body mass index in women with polycystic ovary syndrome | ||
| Iraqi Journal of Embryos and Infertility Researches | ||
| Article 1, Volume 2, Issue 3, June 2012, Pages 16-21 | ||
| Abstract | ||
| Background Elevated serum concentrations of testosterone is common in women with polycystic ovary syndrome (PCOS)but it's relation to body massindex(BMI),isstillunknown. Objective The present study was conducted to investigate the relationship between testosterone level and body mass index in women with polycysticovary syndrome. Methods A total of eighty PCOS women with average age 27.6±0.7 and BMI 31,9±0.5 were compared with twenty-two healthy women considered as a control group (age 28.2±1.1, BMI 28.8±1.0). Patients and controls were grouped according to (BMI: Lean, overweight and obese. All women in both groups were subjected to the following investigations: evaluation of luteinizing hormone (LH), follicle stimulating hormone (FSH.), prolactin (PRL), testosterone levels and ultrasonography. Results The serum levels of LH, LH/FSH and testosterone were significantly higher (P< 0.05) in PCOS compared to control women .while in FSH and PRL the difference was non significant. Obese women with PCOS also had a significantly higher (P<0.05) mean level of testosterone (1.33±0.28ng/ml) compared to lean and overweight patients (0.53±0.17, 0.61±0.08 ng/ml respectively). Ultrasound examination was performed in the ovulatory phase during (12-14) days of the cycle in both PCOS patients and controls, and all women with PCOS with evidence of polycystic ovaries on ultrasonography. Conclusion Testosterone level was significantly elevated in obese compared to overweightand lean women with PCOS .The role of weight reduction is more beneficial in the management of PCOS and improvement of testosterone level. | ||
| Keywords | ||
| Polycysticovary syndrome; FSH; Body mass index | ||
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