Synthesis of Heterocyclic Compounds of Cyclohexenone Derived From Chalcone of Acetophenone | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 23, Issue 7, October 2012, Pages 99-106 | ||
| Author | ||
| Nabil B. Ayrim | ||
| Abstract | ||
| Derivatives of cyclo hexenone were prepared from addition of ethylacetoacetate to chalcone compound which was prepared from the reaction of acetophenone or it's derivatives with benzaldehyde in ethanol in presence of 40 % NaOH . The synthesized cyclo hexenone was treated with hydrazine hydrate to prepare carbohydrazide derivative , which was treated with formic acid , acetic acid , chloro isothiocyante , ethyl acetoacetate and acetyl acetone to prepare new important derivatives with expected biological activity . The structures of the synthesized compounds were confirmed through their physical properties and spectral data | ||
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