Bacteriological study of Septicemia in Neonateat Baghdad pediatric hospitals | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 23, Issue 7, October 2012, Pages 49-56 | ||
| Author | ||
| Waseem Faeq Mohammed | ||
| Abstract | ||
| A total of hundred patients of neonate below twenty eight days which Suspected have septicemia, clinically diagnosed by pediatric physicians in Baghdad pediatric hospitals from Oct 2010 to Aug 2011. The results have revealed that 34 % gave blood culture positive whereas 66 % gave no growth. among 34 positive blood culture cases 61.76% were males and 38.24% were females so males were higher number in compared to females, 70.59% belonged to late onset neonatal sepsis (LONS) and 29.41% belonged to early onset neonatal sepsis (EONS). So the incidence was higher in LONS than EONS. 58.82% were of low birth weight (LBW) and 41.18% were of normal birth weight (NBW) so the incidence of neonatal septicemia was higher in LBW neonates compared to NBW. 64.70% preterm and 35.30% were term. The incidence of preterm neonates was higher compared with term neonates. Bacteria were isolated and diagnosed by using culture media some biochemical tests then identified by Analytic Profile Index (API) system. The Gram positive isolates were Staphylococcus aureus (17.64%), Staphylococcus epidermidis (14.71%), Staphylococcus capitis (11.76%), Staphylococcus hominis (5.88%) and Staphylococcus xylosus (2.94%). While Gram-negative bacteria were Escherichia coli (11.76%), Enterobacter cloacae (8.82%), Klebsiella pneumoniae (8.82%), Pseudomonas aeruginosa (5.88%), Pasteurella spp (5.88%), Burkholderia cepacia (2.95%), Serratia marcescens (2.95%). Burkholderia cepacia is isolated from NNS for the first time in Baghdad accordingly to our information subject. Antibiotic sensitivity was detected by using Kirby-Bauer Method and the zones of inhibition determined by CLSI 2011. ). Staphylococcus spp. resist to Oxacillin were higher than Gentamicin. While all strain were sensitive to Vancomycin. Enterobacteriaceae (Escherichia coli, Enterobacter cloacae, Klebsiella pneumonia and Serratia marcescens ) showed remarkable resistancy to Ampicillin (AMP), Cefazolin (CZ) and Cefotaxime (CTX) while no resistancy to Imipenem (IMP) and Amikacin(AK). Pasteurella spp were sensitive to most antibiotics. Pseudomonas aeruginosa were sensitive to CAZ, IMP and AK while half of isolate resist Piperacillin, PIT, GEN and CIP. Burkholderia cepacia were sensitive to CAZ, IMP and resist to Trimethoprim-sulfamethoxazole, GEN and Chloramphinicol. Key words septicemia, neonates, Neonatal sepsis NNS, late onset neonatal sepsis (LONS) early onset neonatal sepsis (EONS) | ||
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