A Comparison Study of the Inhibitory Effect Between Tin and Ame'tycine on the Adenosine Deaminase (ADA) Activity in Sera of Anemia, Rheumatiod Arthritis and in both . | ||
Tikrit Journal of Pure Science | ||
Article 1, Volume 17, Issue 4, December 2012, Pages 63-66 | ||
Authors | ||
Susan J Ali; Wasan N Al- Assi | ||
Abstract | ||
In this work a comparsion study was carried out of the effect of 0.025M of Tin and Ame'tycine on Adenosine deaminase (ADA) activity in patient's sera of Anemia, Rhematiod Arthritis andin both diseases.The activity percentage after inhibition by Tin were 12.4%, 22.7% and 61.4% while by Ame'tycine were 22.5%, 44.9% and 74.6% in the cases of Anemia, RheumatiodArithritis and in both, recepectively, indicating that Ame'tycine was more potent inhibitor than Tin in all cases.These results may have important theorpatic implications. | ||
Keywords | ||
Adenosine Deaminase; ADA inhibitors; Ame; Tin as inhibitor; Coformcin; ADA | ||
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