Evaluation of Total Sialic Acid and Lipid Associated Sialic Acid in Serum and Tissue in Patients with Breast Tumor | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 20, Issue 1, June 2007, Pages 45-48 | ||
| Authors | ||
| a Al-Bayati; Jameel Hazza; Khalid Karim Rajab; Khalid Karim Rajab | ||
| Abstract | ||
| Abstract: Background: Total serum sialic acid (TSA) and lipid associated sialic acid (LSA) are found to be increased in different neoplastic diseases. The present study was undertaken to study the changes in the concentration of TSA and LSA in serum and tumor tissue of patients with breast tumors. Methods: TSA and LSA levels have been estimated in serum and tissue of patients with breast tumors (n=28) in addition to healthy controls (n=34). Results: Data analysis reflects a significant increase (p<0.05) in the TSA and LSA in the sera and malignant tumor tissue of patients as compared with healthy controls. Conclusions: TSA reflects the development of malignancy and can be considered as supporting tumor marker in malignant breast tumors. Keywords: Breast tumor; cancer; sialic acid; lipid-associated sialic acid. | ||
| Keywords | ||
| Breast tumor; Cancer; sialic acid; Lipid; associated sialic acid | ||
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