The role of sustained-released alfuzosin in the treatment of acute urinary retention | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 18, Issue 182, December 2012, Pages 67-72 | ||
| Author | ||
| Mohamed Fawzi Ahmed | ||
| Abstract | ||
| To see whether the use of alfuzosin 10 mg will increase the success rate of trial without catheter (TWOC) after an attack of acute urinary retention (AUR) related to benign prostatic hyperplasia (BPH). One hundred patients with acute urinary retention due to BPH were consented and enrolled in this prospective ,randomized ,placebo-controlled trial. After catheterization, 50 patients were given sustained release alfuzosin 10 mg once daily ,while the other 50 received placebo. The catheter was removed after three days of treatment for trial without catheter (TWOC). The main outcome measurements were success or failure of TWOC. After removal of the catheter, 64% of patients receiving alfuzosin voided successfully compared to 36% of patients on placebo; the differences being statistically significant at (p<0.05). The mean age of patients who successfully voided, regardless of treatment, was 67.6 years and 69.7 years for those who failed to void which is statistically not significant. Regarding retention volume, there was a significant difference (p<0.05) between the two groups (887.5 ml vs. 994.4 ml). The present tudy coclude that trial without catheter after three days of catheterization is a good practice for BPH men with AUR . However, using alfuzosin 10 mg once daily prior to catheter removal considerably increased the chance of successful TWOC especially if used in patients with low retention volume and younger age group. | ||
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