Modification of Poly(vinyl chloride) via introducing of pendent thiadiazole derivatives and study their Biological Activity | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 23, Issue 2, March 2012, Pages 39-54 | ||
| Author | ||
| Olfa A.Naif | ||
| Abstract | ||
| The present work consist of modification of poly (vinyl chloride) by introduce of pendent thiadiazole which mercapto and amino groups were synthesized in this work according to the following: 1) Reaction of PVC with 2-amino-5-thiol-1,3,4-thiadiazole [I] in THF solvent afforded the following modified polymer (P1) 2) Treatment of PVC with2-Amino-5-ethyl thio-1,3,4-thiadiazole [II] in THF solvent furnishes the modified polymer (P2) 3) Reaction of PVC polymer with 2[4-dimethyl amino benzylidine] 5-thiol- 1,3,4-thiadiazole yields the modified PVC polymer (P3) Structures of all these thiadiazole deravitives and modified polymers have been confirmed by spectral ( FT-IR,UV and H-NMR) analysis. The newly synthesized compounds were subjected to in vitro against two strains of pathogenic microorganism Staphylococcus arueus and Escherichia coli | ||
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