First trimester spontaneous abortion: a clinicopathological view | ||
| Diyala Journal For Pure Science | ||
| Article 1, Volume 8, Issue 3, September 2012, Pages 159-174 | ||
| Author | ||
| Sarmad Raheem Kareem | ||
| Abstract | ||
| A study of 24 cases of first trimester spontaneous abortions and ten normal ongoing first trimester pregnancies are included. Clinical information (maternal age, gestational age, gravidity, parity, history of prior live or dead babies, residency, history of other diseases, infectious and non infectious.) and laboratory assessment of the cases (complete blood count, biochemical assay of serum malondialdehyde level and pathological confirmation of abortion with measurement of trophoblastic villous diameter).Most cases were found to be within the age group (30-39 years) with higher gravidity and history of previous abortion. Hematological profile( except ESR) and serum malondialdehyde show no significant difference between abortion cases and those with normal first trimester pregnancy, but the malondialdehyde level have a strong statistical relation with trophoblastic villous diameter indicating the possibility of underlying relationship between oxidant injury and villous diameter leading to hydropic or even molar changes. | ||
| Keywords | ||
| abortion; Malondialdehyde; trophoblastic villi | ||
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