Association between vaginitis caused by staphylococcus aureus, E.coli and candida albicans and pap smear results | ||
| Al-Qadisiah Medical Journal | ||
| Article 1, Volume 8, Issue 1, June 2012, Pages 102-110 PDF (0 K) | ||
| Authors | ||
| Humady Al-Hillali; Niran Abdul Hussien; Awas Al- Obaidi; Abdul Adheem Jasem | ||
| Abstract | ||
| In this study, one-hundred vaginal swabs and cervical smears were obtained randomly from women admitted to Al-Diwaniya Maternity and Pediatrics Teaching Hospital in Al-Qadisyia Province; samples from private clinics were also included. The samples were taken from married women. Women who were pregnant, with vaginal bleeding, and who recently have used vaginal suppositories were excluded from the study. The samples were collected from November, 2010 to March, 2011. The study involved culturing and isolation of most common microorganisms that cause vaginitis and their association with cellular changes of the cervix. The most common organisms isolated were Staphylococcus aureus( 29.7%) , Escherichia coli (17.6%),and Candida albicans (25.7%). These isolates were associated with cellular changes in (27.2%),(46%), and (21.1%) respectively. In comparison with patients' culture results that revealed normal flora (11%), Pap smear results were normal. The study conclude that any persistent inflammation of the cervix induced by infectious or non-infectious agents and remain untreated will progress into cervical dysplasia and then into cervical cancer. . This may be explained, when cervical metaplasia disrupted by external influences leads to disordered squamous epithelium called dysplastic epithelia. Also cytokines that are released after stimulation of immune response that is caused by bacterial infections or inflammation of various origins may have mutagenic effect and contribute to carcinogenic changes. | ||
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