The effect of atropine on heart rate with rapid sequence induction in neonates | ||
| Mustansiriya Medical Journal | ||
| Article 1, Volume 11, Issue 2, December 2012, Pages 53-57 | ||
| Author | ||
| Ahmed Haki Ismael Al-Rawee | ||
| Abstract | ||
| Background: neonates experience physiological responses to endotracheal intubation, including bradycardia and oxygen desaturation. The bradycardia may be associated with severe hemodynamic disturbances like significant hypotension which may threaten patient's safety. Aims: To determine the effectiveness of single dose IV atropine, 5 minutes before induction of anesthesia on reflex bradycardia to laryngoscopy in sick neonate baby. Patients and Methods: In a randomized double blinded, placebo controlled clinical trial, thirty neonates aged 1-10 days, term, 2.5-3.5kg and from both sexes, were enrolled to receive 0.02mg/kg IV atropine (n=15), as study group and placebo group had received equivalent volume of normal saline five minutes before induction of anaesthesia (n=15), as control group. The induction technique was the same in all patients. The incidence of bradycardia just after intubation was recorded. Results: data analyses showed that the overall incidence of bradycardia just after intubation in the study group was significantly lower than the control group. Conclusions: A single dose IV atropine five minutes before induction of anaesthesia in neonate baby significantly decreases the incidence of bradycardia after intubation. | ||
| Keywords | ||
| Neonates; Bradycardia; Atropine; Rapid sequence induction; Endotracheal intubation | ||
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