Polycondensation of Allopurinol with EDTA and CDTA as Chelation Polymers for Transition Metals | ||
| Iraqi National Journal Of Chemistry | ||
| Article 1, Volume 0, Issue 47, September 2014, Pages 370-377 | ||
| Authors | ||
| Firyal M.Al-Salami; Haider Hatam Rashed | ||
| Abstract | ||
| Abstract Chelation polymers for transition metals were prepared by copolymerization of Allopurinol, a known drug for the treatment of gout and hyperuricaemia, with ethylendiaminetetraacetic acid (EDTA) or cyclohexyldiaminetetraacetic acid (CDTA). The prepared condensed polymers were characterized by using the following spectrometric techniques: UV-visible, 1H-NMR and FT-IR. Their thermal behavior were studied by using thermogravimetric analysis, The intrinsic viscosities in DMF were calculated, and their % swelling in water was measured at 30°C.Their softening point were measured, Also the carboxylic acid functional groups content were measured by acid-base titration. When they were polymerized with as a diamine drug compound; these new drug polymers were modified with metal ions as good ligand, which could be complexes with many poison metal ions. | ||
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