Zinc, Copper, and Superoxide Dismutase in Spermatozoa of Patients with Asethenospermia | ||
| Kerbala Journal of Medicine | ||
| Article 1, Volume 2, Issue 4, August 2009, Pages 420-428 PDF (0 K) | ||
| Authors | ||
| Dr.Mahmoud H. Hadwan; Ferdous A. Jabir; Aqeel H. Tarish; Jabir A. Jabir | ||
| Abstract | ||
| objective:To determine the level of Superoxide dismutase (SOD), Zinc and Copper in the seminal and spermatozoal of patients with asthenospermia. Setting: All semen samples were collected in the infertility unit of the laboratory (in Amel clinic for detection and treatment of infertility/Iraq. Hilla city) after a 3-5 day period of sexual abstinence, then incubated at 37°C and analyzed within 1 h. Methods:The study was conducted on 30 patients and compared to 20 controls. Statistical analysis between group 1 (controls) and group 2 (patients) was performed by the student's t - test. Zinc and copper content was assayed by atomically spectrophotography,SOD enzyme was measured by biochemical assay. This work was undertaken to assess oxidative stress and antioxidant. Results: It was observed that there was a significant increase in seminal and spermatozoal superoxide dismutase activity and copper content. While Zinc were significantly decreased. Conclusions :The results of this study suggest higher oxygen-free radical production, evidenced by increased superoxide dismutase activities, support to the oxidative stress in asthenospermia. The increased activities of antioxidant enzyme may be a compensatory regulation in response to increased oxidative stress. Keywords:Zinc,Copper,Superoxide dismutase(SOD),Human sperm | ||
| Keywords | ||
| Zinc; copper; superoxide dismutase; Human sperm | ||
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