Immunohistochemical detection of the expression of the cell adhesion molecules ICAM-1 & VCAM-1 in Pyogenic granuloma | ||
MUSTANSIRIA DENTAL JOURNAL | ||
Article 1, Volume 3, Issue 4, December 2006, Pages 336-341 | ||
Authors | ||
Dr. Wasan Hamdi Younis B.D.S; ; ; Dr. Natheer H.Al-Rawi. B.D.S; ; ; ; ; Dr. Aml Hindi Al-Falahi B.Sc | ||
Abstract | ||
Pyogenic granuloma is a relatively common benign vascular lesion of the oral mucosa & skin whose exact cause is unknown. The study of the expression of cell adhesion molecules (ICAM-1 & VCAM-1) in oral pyogenic granuloma was performed. Fifteen formalin- fixed, paraffin-embedded oral pyogenic granuloma were studied using LSAB/HRP immunohistochemical technique. Mild to moderate expressions of cell adhesion molecules was demonstrated among different cell types of pyogenic granuloma suggesting that inflammatory response of gingival tissue against oral antigens (gram negative bacteria) may play a major role in inflammatory neovasculairization & hence pathogenesis of pyogenic granuloma . | ||
Keywords | ||
KEYWORDS; ICAM; VCAM; Pyogenic granuloma | ||
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