Evaluation of toxic effects of two weight reduction pills | ||
| Jornal of Biotechnology Research Center | ||
| Article 1, Volume 6, Issue 2, December 2012, Pages 23-28 | ||
| Authors | ||
| Maha F. Al-Taee; Hadeel Waleed Abdul-Malek; Laheeb Jamal Majeed | ||
| Abstract | ||
| his study involved evaluation of side effects of two weight reduction pills that had been widely distributed in the last period. Two weight reduction compounds are studied, Reductil (containing chemical substances) and Chinese’s weight reduction herbs (containing natural substances). Two doses for each compound are used in this research; 5mg/ml and 0.5mg/ml for Reductil, while 30mg/ml and 10mg/ml for Chinese weight reduction herbs. To evaluate the toxic effects of these compounds, the following parameters were determined which include mitotic index (cytogenetic analysis), serum FSH and LH hormones level (follicles stimulation hormone/FSH and lutenising hormone/LH) and histological examination of female mice ovaries. Control group were treated with PBS for comparison. Results revealed that both compounds showed significant changes with the all studied parameters and at both doses when compared with control and, Reductil was shown to be more toxic than the Chinese herbs. | ||
| Keywords | ||
| weight reduction pills; Reductil; Chinese weight reduction herbs | ||
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