SYNTHESIS AND IDENTIFICATION OF SCHIFF BASES AND BILOGICAL ACTIVITY NEW STUDY | ||
Iraqi Journal of Science | ||
Article 1, Volume 53, Issue 2, June 2012, Pages 230-240 | ||
Authors | ||
Hameed Husein Essa; Farouk Kandil; Ahmad Falah | ||
Abstract | ||
In this work we focused on the synthesis of new Open Schiff bases which were prepared by condensation of salicylaldehyde with both 4,4'-diaminodiphenyl methane,4,4'-diamino diphenyl sulphide,and by condensation of O-vanilin with diethyl ester of terephthalic acid respectively.Also new macrocyclic Schiff Bases were prepared by condensation of 1,6-bis(2-formylphenyl)hexane with thiocarbohydrazid.The Schiff bases were checked by different spectral technique (LC-MS, 1H-NMR, IR). The work was extended to study the effect of the prepared compounds on four different bacteria in order to test there biological activity | ||
Keywords | ||
Open Schiff base; Macrocyclic; Salicylaldehyde; Spectral Technique; Antimicrobial activity | ||
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