Effect of High Dose Injection of Methyl Prednisolone Acetate on some Physiological Parameters in Female Rats. | ||
| Journal of Basrah Researches (Sciences) | ||
| Article 1, Volume 38, Issue 3, September 2012, Pages 73-77 PDF (0 K) | ||
| Author | ||
| Jinan Abdul. K Hilal | ||
| Abstract | ||
| This study was conduct on 20 healthy female rats. Ten rats were injected intramuscularly with highly single dose (30mg /kg B.W) of methyl prednisolone acetate (MPA) daily for 60 days. While the other ten injected intramuscularly with normal saline (1ml/kg B.W) and considered as a control. Blood samples were collected from treated and control rats as well. Results revealed that there was significant (p<0.05) decrease in, total serum protein , lymphocytic count ,esinophilic and basophilic counts . There were significant (p< 0.05) increase in estrogen, progesterone, tri-iodthyronine(T3) , thyroxine(T4) hormones , total serum cholesterol , triglyceride ,total WBC count, neutrophilic and monocytiz counts . | ||
| Keywords | ||
| Methyl predinsolone acetate; female rats; Hormones; biochemical parameters; WBC; predinsolone WBC | ||
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