Evaluation of some minerals status in patients with thyroid glands disorders | ||
| Mustansiriya Medical Journal | ||
| Article 1, Volume 6, Issue 2, December 2006, Pages 27-36 | ||
| Authors | ||
| Hazim H. Eidan; Adnan Fadhil Ahmed; Mohammed Abdull-Jaleel Ziarah | ||
| Abstract | ||
| Objective: The hormones which were secreting by thyroid gland play a role in regulation of many biological processes, therefore, the disorder in production of these hormones lead to changes in many metabolic and catabolic processes. The aim of this study is to evaluate the status of some minerals, and trace elements in patients with thyroid disorders (hyperthyroidism, hypothyroidism, and treated thyroid cancer). Subjects &protocol: This study includes (125) healthy controls and (125) patients with thyroid disorders were distributed into three groups. The first group includes hyperthyroidism patients, the second includes hypothyroidism patients. Each of these groups include (50) patients newly diagnosed, While the third group includes (25) patients with treated thyroid cancer by surgery. Hormonal assay was done by gamma counter, while minerals and trace elements were determined by spectrophotometer and Combisys II set. Results: Significant increase in serum (Cu) levels of hyperthyroidism patients and significant decrease in hypothyroidism and thyroid cancer patients when compared with normal group 2-. Significant decrease in serum Zn levels of hyperthyroidism patients and significant increase of Zn levels in hypothyroidism and thyroid cancer patients when compared the previous groups with normal group. 3- This study showed significant decrease in serum Fe in all groups of thyroid disorders when compared with normal group. 4- Li levels were significantly decreased in all groups of thyroid disorders patients when compared with normal group. 5- Some data (Fe) levels of thyroidectomy group showed no significant difference when compared with hypothyroidism patients. Conclusion: This study illustrated the role of thyroid disorders in anabolic and catabolic processes of the minerals and trace elements metabolism. To our knowledge (by midline studies, and internet till 2004) this is the first study concerned with the determination of Li level in serum of patients with thyroid disorders in Iraq. | ||
| Keywords | ||
| minerals; Thyroid Gland Disorders | ||
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