The Role of Leptin and Insulin like Growth factor-1 in patients with Thyroid dysfunction | ||
| Mustansiriya Medical Journal | ||
| Article 1, Volume 11, Issue 1, June 2012, Pages 58-62 | ||
| Author | ||
| Huda H. Hassan | ||
| Abstract | ||
| Aims: To evaluate the relationship between serum Leptin, Growth factor-1 (IGF-1) levels and untreated thyroid dysfunction patients. Patients and Methods: A study was made on 50 untreated goiterous patients (female and males) with range between (25-55) years; and25 controls subjects (females and males) with range between (14-55) years. Serum T3, T4 &TSH were by Radio immune assay (RIA) method. Serum Leptin and Insulin like growth factor-1 (IGF-1) was measured by ELISA method. Results: The mean Serum Leptin level was significantly lowest in hyperthyroidism than control subjects. While Insulin growth factor level was significantly highest in hyperthyroidism than control subjects (3.82 vs. 2.49) Conclusions: the objective of the study was to provide new data on the relationship between serum Leptin, Insulin like Growth Factor-1 levels and thyroid dysfunction. | ||
| Keywords | ||
| leptin hormone; Insulin like growth factor; Hormone; Thyroid Hormone; Hyperthyroidism | ||
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