Synthesis and Study the Biological Activity of Some New Isoxathiozolidines by 1,3-Dipolar Cycloaddition of Nitrones and Thioacetamide | ||
| Journal of Univesity of Thi-Qar | ||
| Article 1, Volume 7, Issue 3, September 2012, Pages 1-10 | ||
| Author | ||
| Zainab A. Mohammed Saleh | ||
| Abstract | ||
| A series of new isoxathozolidines (4-6) were synthesized by 1,3-dipolar cycloaddition reaction of different nitrones with thioacetamide under reflux condition . The yields of products following recrystallization from various solvents, and characterized by spectral methods (IR , UV , TLC , M.P), were used for identification of these compounds. The biological activety show that the compounds have antibacterial activity. | ||
| Keywords | ||
| Nitrones; Cycloaddition; Isoxathiozolidines; antibacterial activity | ||
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