Expression of Toll-like Receptor 9 in Iraqi Patients with Systemic Lupus Erythematosus | ||
| Al-Ma'mon College Journal | ||
| Article 1, Volume 0, Issue 19, April 2018, Pages 39-48 | ||
| Authors | ||
| Noorriyya A. Ali; Batool A. Ahmaed; Raya E. AL-saade | ||
| Abstract | ||
| Toll-like receptors (TLRs) are classes of single membrane-spanning non-catalytic receptors that structurally recognize a molecules which is derived from microbes once these microbes have breached physical barriers such as the skin or the intestinal tract mucosa and activated the immune cell response . TLR9 expression on B cells have been estimated for 54 of Systemic Lupus Erythematosus (SLE) patients, 30 Rheumatoid Arthritis (RA) patients compared to 30 Healthy Control(HC) by immunofluorescence using monoclonal anti-CD289 FITC labeled protein against human TLR9.The study showed that B cell expression of TLR9 was higher among SLE patients than RA patients and healthy control groups with means of frequency positivity (34.8 , 31.1 and 26.7 respectively) and p =0.02 . | ||
| Keywords | ||
| Erythematosus; Toll; like Receptor; Systemic; Lupus | ||
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