Renal dysfunction after major surgical operation : the impact of age, gender, and obesity | ||
| KUFA MEDICAL JOURNAL | ||
| Article 1, Volume 15, Issue 1, June 2012, Pages 395-407 | ||
| Author | ||
| Dr.Abdul - Aziz Ahmed Aziz | ||
| Abstract | ||
| Aim: To study the effect of major surgical operation on renal function and to evaluate the role of age, gender and body weight. Methods: seventy patients (39 males, and 31females) aged (20-60 years), who admitted to Al-Sader Teaching hospital for major surgical operation in Al- Nagaf Al-Ashraf, from October 2009 to September 2010. For every patient participate in the study plasma concentration of sodium, creatinine, urea, urine sodium , urine creatinin, creatinine clearance and fractional excretion of sodium were determined. Results: The were statistically significant increase in plasma level of creatinine, urea, and fractional excretion of sodium ( P≤ 0.001, P≤ 0.0001 and P≤ 0.0001) and statistically significant decrease in creatinine clearance ( P≤ 0.0001) after surgical operation in comparison with preoperative values in elderly patients(41 - 60 years). A similar statistically significant changes observed in obese patients when preoperative values are compared with postoperative values. While there was no significant changes in the preoperative and postoperative values of these parameters in younger age groups(20-40 years) or when patients classified into males and females. Conclusion: major surgical operation had significant effect on renal function, specially on elderly and obese patients. | ||
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