Molecular Diagnosis, Detection and Treatment of Drug Resistant Mycobacterium tuberculosis | ||
| KUFA MEDICAL JOURNAL | ||
| Article 1, Volume 15, Issue 1, June 2012, Pages 299-313 | ||
| Author | ||
| Dr. Zuhair Saleh Allebban | ||
| Abstract | ||
| Tuberculosis has affected humans for centuries and the number of mycobacterium tuberculosis infections have been shown to be increasing worldwide, mainly due the increased number of patients with HIV infection and AIDS disease worldwide, an increasing number of elderly patients and the emergence of multidrug resistant tuberculosis. The disease is caused by a bacterium called Mycobacterium tuberculosis (MT) and is also called tubercle bacilli (TB). Inhalation is the predominant pathway of MT infection, making pulmonary tuberculosis the most common form of tuberculosis. Tuberculosis may arise either from a recent infection with MT, or from the reactivation of dormant bacilli, years or decades after initial infection. Extrapulmonary tuberculosis mainly results from reactivation of a tuberculous focus after hematogenous dissemination or lymphogenous spread from a primary, usually pulmonary focus. Tuberculosis may demonstrate a variety of radiological features depending on the organ site involved and may mimick other pathologies. The final diagnosis of tuberculous | ||
| Keywords | ||
| Molecular diagnosis; tuberculosis; drug resistance | ||
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