Spermatozoal creatine kinase (CK) concentration as an indication of idiopathic obese subfertile males with normozoospermia | ||
| KUFA MEDICAL JOURNAL | ||
| Article 1, Volume 15, Issue 1, June 2012, Pages 196-203 | ||
| Authors | ||
| ; ; Ph. D; ; Najah R. Haddi; ; ; ; Noorhan Shakir Mhao; Ahmed S. Al-Hilli. Med MSc. Ph .D | ||
| Abstract | ||
| Objective: To determine the mean of spermatozoal creatine kinase (CK) concentration in idiopathic obese subfertile males with normozoospermia and healthy normal fertile control group. And to compare spermatozoal CK concentration between idiopathic obese normozoosperpmic subfertiles and healthy normal fertile volunteers (control group). Design: A prospective study. Setting: Maternity and Childhood Hospital, Najaf province, during period from April 2006 to January 2007. Patients and Methods: The present study determined the mean of spermatozoal CK concentration in 47 idiopathic obese male subfertiles with normozoospermia ,their ages ranging between 25-45 years ,and sperm count million ml, motility% , morphology %, vitality% are registered as normozoospermia according to WHO criteria. Fifteen apparently healthy normal fertile were regarded as control group. Traditional semen analyses and sperm parameters were assisted by same examiner. CK concentrations were measured using CK kit after the sperm enzyme was extracted within triton –X. The results of spermatozoal CK concentration was determined and compared between both groups. Result(s): There was a statistically significant differences (P<0.05) in active sperm motility % and sperm immotility % in comparison to sperm mean CK concentration in both groups. And sperm mean CK concentration was significantly higher in idiopathic obese male subfertiles with normozoospermia in comparison to control group. Conclusion(s): Elevated levels of spermatozoal CK concentration in idiopathic normozoospermic obese subfertile males may suggest an indication of sperm oxidative stress status which could play a role in idiopathic normozoospermic obese subfertility and fecundity that warrants more detail studies. Recommendation(s): creatine kinase concentration could be use an indication of sperm oxidative stress in idiopathic obese subfertile males with normozoospermia | ||
| Keywords | ||
| Creatine kinase; idiopathic subfertility; Obesity | ||
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